Dark Bio Blog

Devcon 8, It's a Wrap!

Sun, 08 Nov 2026 00:00:00 +0000

12 years of Devcon (/connect) attendance, first time representing Dark Bio! It has been a wonderful event like always, kudos to the organizer team, the volunteers and everyone coming to Mumbai to meet and greet.

We’ve been given the opportunity to do a few talks, and ended up accepting two slots only, to keep our own sanity :D Apologies for the ones we turned down, we really appreciated the possibility!

ArkOS 0.13: Variants and Samples

Tue, 20 Oct 2026 00:00:00 +0000

We’ve just released ArkOS 0.13.1, along with a large set of associated tooling. For the observant among you, we skipped 0.13.0. It was signed, but a last-minute API change made us pull it.

ArkOS 0.13.1 is a significant feature release. It ships support for the structural and copy number genomic variant files; extends the biofs API surface and example apps with new types of genomic queries. Comes with tools that can seed an Ark with any of 3,202 sample genomes for testing.

Dark Bio Platform Hands-on

Mon, 12 Oct 2026 00:00:00 +0000

Dark Bio has been in development for quite a while now, so we’ve figured it is an opportune moment to reveal more on where we are, where we are going, and what you can play with… today.

TL;DR: ChatGPT turns a Nature paper¹ into an analysis against my genome.

The above demo is pretty much the end-game of the Dark Bio platform. While it works, there is a lot of magic going on behind the scenes. So let’s try to unpack it from the ground up.

Quantum Threat, Today

Fri, 13 Feb 2026 00:00:00 +0000

Quantum computers are the new boogie-man everyone in tech is afraid of. But if such computers can potentially solve many of humanity’s hardest problems (like weather prediction), why are they such a scary thing? Well, it turns out, humanity has a few self-made “problems” that we’ve explicitly designed to be hard; and we really don’t like it, that quantum computers solve those too! Namely, cryptography.

The above video is a Ted talk. It’s a nice introduction for someone with no engineering background to feel the magnitude of the problem; but it raises more questions than it answers. We need a bit more nuance instead of saying that quantum computers will break all modern cryptography.

Leaky LLMs: Accident or Nature?

Mon, 09 Feb 2026 00:00:00 +0000

Approximately two weeks ago, OpenClaw (originally Clawdbot renamed MoltBot) became an overnight sensation. It allowed anyone to run their own proactive AI agent, which could just do stuff without having to be prompted. This had a huge appeal in itself, but was even further exacerbated by the appearance of moltbook, a kind of Reddit/Facebook mix for AI agents. People went wild, a lot of money was made, a lot of agents were launched. On the one hand, it is an amazing and fun development. On the other, it’s a catastrophe waiting to happen. Problem is, people don’t understand the tech yet, but have a big fear of missing out on it.

Whole Genome Sequencing - 101

Thu, 01 Jan 2026 00:00:00 +0000

The “science” of longevity is living its renaissance. Countless doctors, nutritionists and even influencers are preaching the best way to achieve your longest lifespan and best health-span. They have everything figured out, ranging from the perfect exercise routine, through the perfect diet and supplementation, down to the exact protocol for even less-understood substances.

The problem is, it’s not easy to find two, who agree on all those details. We all have that one friend who swears on the carnivore diet; but also the other one, who never ate meat in their life. We have that friend who does crossfit five times per week, and the other whose peak workout is the trip from the bed to the computer - yet is fit as ever. Thing is, each of us is unique and what might work for some, could possibly fail for another.